MLPA® - MRC Holland Kits
Please note before download:
- Mix descriptions are only free of charge for customers with maintenance contract.
- Don't hesitate to contact us, if there are any mix descriptions missing on this website.
-
To set up a new mix descriptions for you, still available at MRC Hollands website, please provide us the name of the mix (e.g. P002-D1), the version of the mix (e.g. Vs.02) and the date of its release.
- To set up a new mix descriptions for you, not available at MRC Hollands website any more, please provide us the corresponding document by email or fax (+49-7822-440150-20).
Download
- log into your SEQUENCE Pilot installation
- go to category MLPA®
- go to operation Mixes [master file]
- press button [Import] and select the downloaded mme-file
- if the corresponding mix already exists in your SEQUENE_PILOT installation you will be asked "Do you want to save the mix with a new name / lot?"; please press button [Yes] and complete the fields in the following dialogue; press button [OK] to save your entries
- if the mix doesn't exist yet just press button [OK] in the following dialogue
MIX
VERSION
DATE
REGION
APPLICATION
DOWNLOAD
MIX
P002-D1
VERSION
Vs. D1-05
DATE
09-01-2019
REGION
BRCA1, 17q21
APPLICATION
Breast cancer, hereditary
MIX
P002-D1
VERSION
Vs. D1-06
DATE
27-04-2020
REGION
BRCA1, 17q21
APPLICATION
Breast cancer, hereditary
MIX
P002-D1
VERSION
Vs. D1-07
DATE
15-02-2021
REGION
BRCA1, 17q21
APPLICATION
Breast cancer, hereditary
MIX
P002-D1
VERSION
Vs. D1-08
DATE
07-06-2021
REGION
BRCA1, 17q21
APPLICATION
Breast cancer, hereditary
MIX
P002-D1
VERSION
Vs. D1-09
DATE
01-12-2022
REGION
BRCA1 17q21.31
APPLICATION
Breast and ovarian cancer syndrome, hereditary (HBOC)
MIX
P002-D1
VERSION
Vs. D1-10
DATE
12-01-2023
REGION
BRCA1 17q21.31
APPLICATION
Breast and ovarian cancer syndrome, hereditary (HBOC)
MIX
P002-D1
VERSION
Vs. D1-11
DATE
05-04-2023
REGION
BRCA1 17q21.31
APPLICATION
Breast and ovarian cancer syndrome, hereditary (HBOC)
MIX
P003-D1
VERSION
Vs. D1-03
DATE
28-11-2017
REGION
MLH1 3p21.3, MSH2 2p22
APPLICATION
Hereditary nonpolyposis colon cancer (HNPCC)
MIX
P003-D1
VERSION
Vs. D1-04
DATE
02-08-2018
REGION
MLH1 3p21.3, MSH2 2p22
APPLICATION
Hereditary nonpolyposis colon cancer (HNPCC)
MIX
P003-D1
VERSION
Vs. D1-05
DATE
22-06-2020
REGION
MLH1 3p22.2; MSH2 2p21
APPLICATION
Lynch syndrome
MIX
P003-D1
VERSION
Vs. D1-06
DATE
29-10-2021
REGION
MLH1 3p22.2; MSH2 2p21
APPLICATION
Lynch syndrome
MIX
P003-D1
VERSION
Vs. D1-07
DATE
24-02-2023
REGION
MLH1 3p22.2; MSH2 2p21
APPLICATION
Lynch syndrome
MIX
P008-C1
VERSION
Vs. C1-02
DATE
30-07-2018
REGION
PMS2 7p22
APPLICATION
Hereditary nonpolyposis colon cancer (HNPCC)
MIX
P008-C1
VERSION
Vs. C1-03
DATE
11-05-2020
REGION
PMS2 7p22
APPLICATION
Hereditary nonpolyposis colon cancer (HNPCC)
MIX
P008-C1
VERSION
Vs. C1-04
DATE
22-03-2021
REGION
PMS2 7p22.1
APPLICATION
Lynch syndrome; Constitutional MMR-deficiency syndrome (CMMR-D)
MIX
P008-C1
VERSION
Vs. C1-05
DATE
04-11-2021
REGION
PMS2 7p22.1
APPLICATION
Lynch syndrome; Constitutional MMR-deficiency syndrome (CMMR-D)
MIX
P010-A3
VERSION
Vs. 06
DATE
15-01-2014
REGION
POLG, POLG2, C10orf2 (PEO1), SLC25A4 (ANT1)
APPLICATION
Mitochondrial maintenance
MIX
P010-A4
VERSION
Vs. 07
DATE
28-02-2017
REGION
POLG, POLG2, C10orf2 (PEO1), SLC25A4 (ANT1)
APPLICATION
Mitochondrial maintenance
MIX
P010-B1
VERSION
Vs. B1-01
DATE
16-11-2020
REGION
POLG 15q26.1; POLG2 17q23.3; TWNK (C10orf2) 10q24.31; SLC25A4 (ANT1) 4q35.1
APPLICATION
Mitochondrial maintenance
MIX
P011-B2
VERSION
Vs. 05
DATE
20-12-2012
REGION
vWF 12p13
APPLICATION
Von Willebrand Disease (vWD)
MIX
P011-B3
VERSION
Vs. 07
DATE
26-05-2016
REGION
vWF 12p13
APPLICATION
Von Willebrand Disease (vWD)
MIX
P011-B4
VERSION
Vs. B4-01
DATE
20-03-2020
REGION
VWF 12p13.31
APPLICATION
Von Willebrand disease (vWD)
MIX
P012-B3
VERSION
Vs. 07
DATE
26-05-2016
REGION
vWF 12p13
APPLICATION
Von Willebrand Disease (vWD)
MIX
P012-B3
VERSION
Vs. 08
DATE
26-04-2018
REGION
vWF 12p13
APPLICATION
Von Willebrand Disease (vWD)
MIX
P012-B4
VERSION
Vs. B4-01
DATE
20-03-2020
REGION
VWF 12p13.31
APPLICATION
Von Willebrand disease (vWD)
MIX
P012-B4
VERSION
Vs. B4-02
DATE
27-07-2022
REGION
VWF 12p13.31
APPLICATION
Von Willebrand disease (vWD)
MIX
P013-A2
VERSION
Vs. 05
DATE
20-01-2015
REGION
ATRX; Xq13
APPLICATION
Alpha-Thalassemia/Mental Retardation
MIX
P013-A2
VERSION
Vs. A2-01
DATE
21-11-2018
REGION
ATRX Xq21.1
APPLICATION
Alpha-thalassemia X-linked intellectual disability syndrome (ATRX)
MIX
P013-A2
VERSION
Vs. A2-02
DATE
11-11-2021
REGION
ATRX Xq21.1
APPLICATION
Alpha-thalassemia X-linked intellectual disability syndrome (ATRX)
MIX
P015-F2
VERSION
Vs. F2-03
DATE
18-05-2020
REGION
MECP2 Xq28; CDKL5 Xp22.13; ARX Xp21.3; NTNG1 1p13.3
APPLICATION
RETT syndrome, classic; RETT syndrome, atypical; MECP2 duplication syndrome; X-linked intellectual disability syndrome
MIX
P015-F2
VERSION
Vs. F2-04
DATE
16-03-2021
REGION
MECP2 Xq28; CDKL5 Xp22.13; ARX Xp21.3; NTNG1 1p13.3
APPLICATION
RETT syndrome, classic; RETT syndrome, atypical; MECP2 duplication syndrome; X-linked intellectual disability syndrome
MIX
P015-F2
VERSION
Vs. F2-05
DATE
25-08-2021
REGION
MECP2 Xq28; CDKL5 Xp22.13; ARX Xp21.3; NTNG1 1p13.3
APPLICATION
RETT syndrome, classic; RETT syndrome, atypical; MECP2 duplication syndrome; Early infantile epileptic encephalopathy
MIX
P015-F2
VERSION
Vs. F2-06
DATE
21-03-2023
REGION
MECP2 Xq28; CDKL5 Xp22.13; ARX Xp21.3; NTNG1 1p13.3
APPLICATION
RETT syndrome, classic; RETT syndrome, atypical; MECP2 duplication syndrome; CDKL5 deficiency disorder; Early infantile epileptic encephalopathy 1
MIX
P015-F2
VERSION
Vs. F2-07
DATE
16-11-2023
REGION
MECP2 Xq28; CDKL5 Xp22.13; ARX Xp21.3; NTNG1 1p13.3
APPLICATION
RETT syndrome, classic; RETT syndrome, atypical; MECP2 duplication syndrome; CDKL5 deficiency disorder; Early infantile epileptic encephalopathy 1
MIX
P016-C2
VERSION
Vs.C2-02
DATE
20-04-2017
REGION
VHL, 3p25
APPLICATION
Von Hippel-Lindau Syndrome
MIX
P016-C2
VERSION
Vs.C2-03
DATE
18-04-2019
REGION
VHL
APPLICATION
Von Hippel-Lindau Syndrome
MIX
P016-C2
VERSION
Vs.C2-04
DATE
29-06-2021
REGION
VHL 3p25.3
APPLICATION
Von Hippel-Lindau syndrome
MIX
P016-C2
VERSION
Vs.C2-05
DATE
05-12-2023
REGION
VHL 3p25.3
APPLICATION
Von Hippel-Lindau syndrome
MIX
P017-D1
VERSION
Vs. 19
DATE
09-08-2016
REGION
MEN1 11q13
APPLICATION
Multiple endocrine neoplasia
MIX
P017-D1
VERSION
Vs. D1-01
DATE
31-10-2018
REGION
MEN1 11q13
APPLICATION
Multiple endocrine neoplasia
MIX
P017-D1
VERSION
Vs. D1-04
DATE
03-02-2021
REGION
MEN1 11q13.1
APPLICATION
Multiple endocrine neoplasia type 1 (MEN1)
MIX
P018-G2
VERSION
Vs. G2-02
DATE
15-04-2019
REGION
SHOX Xp22
APPLICATION
Idiopathic growth retardation
MIX
P018-G2
VERSION
Vs. G2-03
DATE
27-04-2020
REGION
SHOX Xp22.33/Yp11.32
APPLICATION
Leri-Weill dyschondrosteosis (LWD); Langer mesomelic dysplasia (LMD); Idiopathic short stature (ISS)
MIX
P018-G2
VERSION
Vs. G2-04
DATE
13-11-2020
REGION
SHOX Xp22.33/Yp11.32
APPLICATION
Leri-Weill dyschondrosteosis (LWD); Langer mesomelic dysplasia (LMD); Idiopathic short stature (ISS)
MIX
P018-G2
VERSION
Vs. G2-05
DATE
22-02-2022
REGION
SHOX Xp22.33/Yp11.32
APPLICATION
Leri-Weill dyschondrosteosis (LWD); Langer mesomelic dysplasia (LMD); Idiopathic short stature (ISS)
MIX
P018-G2
VERSION
Vs. G2-06
DATE
21-03-2023
REGION
SHOX Xp22.33/Yp11.32
APPLICATION
Leri-Weill dyschondrosteosis (LWD); Langer mesomelic dysplasia (LMD); Idiopathic short stature (ISS)
MIX
P018-G2
VERSION
Vs. G2-07
DATE
20-03-2024
REGION
SHOX Xp22.33/Yp11.32
APPLICATION
Leri-Weill dyschondrosteosis (LWD); Langer mesomelic dysplasia (LMD); Idiopathic short stature (ISS)