MLPA® - MRC Holland Kits

Please note before download:

  • Mix descriptions are only free of charge for customers with maintenance contract.
  • Don't hesitate to contact us, if there are any mix descriptions missing on this website.
  • To set up a new mix descriptions for you, still available at MRC Hollands website, please provide us the name of the mix (e.g. P002-D1), the version of the mix (e.g. Vs.02) and the date of its release.

  • To set up a new mix descriptions for you, not available at MRC Hollands website any more, please provide us the corresponding document by email or fax (+49-7822-440150-20).

Download

  • log into your SEQUENCE Pilot installation
  • go to category MLPA®
  • go to operation Mixes [master file]
  • press button [Import] and select the downloaded mme-file
  • if the corresponding mix already exists in your SEQUENE_PILOT installation you will be asked "Do you want to save the mix with a new name / lot?"; please press button [Yes] and complete the fields in the following dialogue; press button [OK] to save your entries
  • if the mix doesn't exist yet just press button [OK] in the following dialogue
MIX
VERSION
DATE
REGION
APPLICATION
DOWNLOAD
MIX
P021-B1
VERSION
Vs. B1-01
DATE
22-11-2018
REGION
SMN1, SMN2, 5q13
APPLICATION
Spinal Muscular Atrophy (SMA)
MIX
P021-B1
VERSION
Vs. B1-02
DATE
05-07-2019
REGION
SMN1, SMN2, 5q13
APPLICATION
Spinal Muscular Atrophy (SMA)
MIX
P021-B1
VERSION
Vs. B1-03
DATE
25-06-2020
REGION
SMN1 5q13.2; SMN2 5q13.2
APPLICATION
Spinal muscular atrophy (SMA)
MIX
P021-B1
VERSION
Vs. B1-04
DATE
28-05-2021
REGION
SMN1 5q13.2; SMN2 5q13.2
APPLICATION
Spinal muscular atrophy (SMA)
MIX
P021-B1
VERSION
Vs. B1-05
DATE
26-04-2022
REGION
SMN1 5q13.2; SMN2 5q13.2
APPLICATION
Spinal muscular atrophy (SMA)
MIX
P021-B1
VERSION
Vs. B1-06
DATE
11-07-2022
REGION
SMN1 5q13.2; SMN2 5q13.2
APPLICATION
Spinal muscular atrophy (SMA)
MIX
P022-B2
VERSION
Vs. 14
DATE
16-01-2015
REGION
PLP1 Xq22
APPLICATION
Pelizaeus-Merzbacher disease (PMD)
MIX
P022-B2
VERSION
Vs. B2-01
DATE
24-05-2018
REGION
PLP1 Xq22
APPLICATION
Pelizaeus-Merzbacher disease (PMD)
MIX
P023B
VERSION
Vs. 09
DATE
20-11-2006
REGION
22q11
APPLICATION
DiGeorge syndrome, Velocardiofacial syndrome (VCFS), Cat eye syndrome (CES)
MIX
P023-B2
VERSION
Vs. 16
DATE
10-06-2008
REGION
22q11
APPLICATION
DiGeorge syndrome, Velocardiofacial syndrome (VCFS), Cat eye syndrome (CES)
MIX
P024-B
VERSION
Vs. 11
DATE
05-05-2008
REGION
CDKN2A / 2B region
APPLICATION
Various types of tumors
MIX
P025-A2
VERSION
Vs. 11
DATE
20-12-2012
REGION
ASPA, 17p13
APPLICATION
Canavan disease
MIX
P025-A3
VERSION
Vs. 12
DATE
16-05-2014
REGION
ASPA, 17p13
APPLICATION
Canavan disease
MIX
P025-A4
VERSION
Vs. A4-01
DATE
03-02-2020
REGION
ASPA 17p13
APPLICATION
Canavan disease
MIX
P026-D2
VERSION
Vs. 10
DATE
21-01-2015
REGION
NSD1, 5q35
APPLICATION
Sotos syndrome
MIX
P026-E1
VERSION
Vs. 11
DATE
08-03-2017
REGION
NSD1, 5q35
APPLICATION
Sotos syndrome
MIX
P026-E2
VERSION
Vs. E2-01
DATE
24-11-2020
REGION
NSD1 5q35; NFIX 19p13
APPLICATION
Sotos syndrome
MIX
P027-C1
VERSION
Vs. 11
DATE
12-08-2011
REGION
1p, 3, 6p, 8q (MYC region)
APPLICATION
Uveal Melanoma
MIX
P027-C1
VERSION
Vs. 14
DATE
24-04-2013
REGION
1p, 3, 6p, 8q (MYC region)
APPLICATION
Uveal Melanoma
MIX
P028-A1
VERSION
Vs. 01
DATE
03-12-2012
REGION
UNC13D 17q25.1, PRF1 10q22.1, STX11 6q24.2
APPLICATION
Familial lymphohistiocytosis (HLH)
MIX
P028-B1
VERSION
Vs. 03
DATE
19-01-2016
REGION
UNC13D 17q25.1, PRF1 10q22.1, STX11 6q24.2
APPLICATION
Familial lymphohistiocytosis (HLH)
MIX
P029-B1
VERSION
Vs. 15
DATE
10-01-2017
REGION
WBS criticial region 7q11.23
APPLICATION
Williams-Beuren syndrome
MIX
P029-C1
VERSION
Vs. 16
DATE
29-05-2017
REGION
WBS criticial region 7q11.23
APPLICATION
Williams-Beuren syndrome
MIX
P029-C1
VERSION
Vs. C1-01
DATE
02-12-2020
REGION
WBS criticial region 7q11.23
APPLICATION
Williams-Beuren syndrome (WBS); 7q11.23 duplication syndrome
MIX
P031-B2
VERSION
Vs. 17
DATE
10-01-2017
REGION
FANCA 16q24.3
APPLICATION
Fanconi Anemia (FA)
MIX
P031-B3
VERSION
Vs. B3-01
DATE
05-03-2019
REGION
FANCA 16q24.3
APPLICATION
Fanconi Anemia (FA)
MIX
P031-B4
VERSION
Vs. B4-01
DATE
04-08-2022
REGION
FANCA 16q24.3
APPLICATION
Fanconi anemia (FA)
MIX
P032-B2
VERSION
Vs. 17
DATE
10-01-2017
REGION
FANCA 16q24.3
APPLICATION
Fanconi Anemia (FA)
MIX
P032-B3
VERSION
Vs. B3-01
DATE
05-03-2019
REGION
FANCA 16q24.3
APPLICATION
Fanconi Anemia (FA)
MIX
P032-B4
VERSION
Vs. B4-01
DATE
04-08-2022
REGION
FANCA 16q24.3
APPLICATION
Fanconi anemia (FA)
MIX
P033-B4
VERSION
Vs. B4-01
DATE
24-06-2016
REGION
CMT1/HNPP region, 17p11.2
APPLICATION
Charot-Marie Tooth disease (CMT1), Hereditary Neuropathy with liability to Pressure Palsies (HNPP)
MIX
P033-B4
VERSION
Vs. B4-03
DATE
25-04-2019
REGION
CMT1/HNPP region, 17p11.2
APPLICATION
Charot-Marie Tooth disease (CMT1), Hereditary Neuropathy with liability to Pressure Palsies (HNPP)
MIX
P033-B4
VERSION
Vs. B4-04
DATE
15-06-2020
REGION
CMT/HNPP region 17p12; KIF1b 1p36
APPLICATION
Charcot-Marie-Tooth neuropathy (CMT); Neuropathy with liability to pressure palsies, hereditary (HNPP)
MIX
P033-B4
VERSION
Vs. B4-05
DATE
06-05-2021
REGION
CMT/HNPP region 17p12; KIF1b 1p36
APPLICATION
Charcot-Marie-Tooth neuropathy (CMT); Neuropathy with liability to pressure palsies, hereditary (HNPP)
MIX
P033-B4
VERSION
Vs. B4-06
DATE
27-01-2023
REGION
CMT/HNPP region 17p12; KIF1b 1p36
APPLICATION
Charcot-Marie-Tooth neuropathy (CMT); Neuropathy with liability to pressure palsies, hereditary (HNPP)
MIX
P034-B2
VERSION
Vs. B2/B1-02
DATE
10-02-2017
REGION
DMD, Xp21.2
APPLICATION
Duchene Muscular Dystrophy (DMD)
MIX
P034-B2
VERSION
Vs. B2/B1-03
DATE
24-10-2018
REGION
DMD, Xp21.2
APPLICATION
Duchene Muscular Dystrophy (DMD)
MIX
P034-B2
VERSION
Vs. B2/B1-04
DATE
13-07-2020
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P034-B2
VERSION
Vs. B2/B1-05
DATE
21-09-2020
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P034-B2
VERSION
Vs. B2-06
DATE
24-03-2021
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P034-B2
VERSION
Vs. B2-07
DATE
16-09-2021
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P034-B2
VERSION
Vs. B2-08
DATE
19-01-2023
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P035-B1
VERSION
Vs. B2/B1-02
DATE
10-02-2017
REGION
DMD, Xp21.2
APPLICATION
Duchene Muscular Dystrophy (DMD)
MIX
P035-B1
VERSION
Vs. B2/B1-03
DATE
24-10-2018
REGION
DMD, Xp21.2
APPLICATION
Duchene Muscular Dystrophy (DMD)
MIX
P035-B1
VERSION
Vs. B2/B1-04
DATE
13-07-2020
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P035-B1
VERSION
Vs. B2/B1-05
DATE
21-09-2020
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P035-B1
VERSION
Vs. B2/B1-06
DATE
24-03-2021
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P035-B1
VERSION
Vs. B2/B1-07
DATE
16-09-2021
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P035-B1
VERSION
Vs. B1-08
DATE
19-01-2023
REGION
DMD Xp21.1-p21.2
APPLICATION
Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD)
MIX
P036-E3
VERSION
Vs. E3-02
DATE
14-12-2017
REGION
all subtelomeres
APPLICATION
Subtelomeric testing
MIX
P036-E3
VERSION
Vs. E3-03
DATE
05-06-2018
REGION
all subtelomeres
APPLICATION
Subtelomeric testing
MIX
P036-E3
VERSION
Vs. E3-04
DATE
17-06-2020
REGION
All subtelomeres
APPLICATION
Subtelomeric testing
MIX
P036-E3
VERSION
Vs. E3-06
DATE
05-04-2023
REGION
All subtelomeres
APPLICATION
Subtelomeric testing
MIX
P037-B1
VERSION
Vs. 20
DATE
17-12-2013
REGION
various
APPLICATION
Chronic Lymphocytic Leukemia (CLL)
MIX
P037-B1
VERSION
Vs. 21
DATE
27-10-2014
REGION
various
APPLICATION
Chronic Lymphocytic Leukemia (CLL)
MIX
P037-B1
VERSION
Vs. B1-01
DATE
23-01-2020
REGION
Various
APPLICATION
Chronic lymphocytic leukemia (CLL)
MIX
P038-B1
VERSION
Vs. 20
DATE
17-12-2013
REGION
various
APPLICATION
Chronic Lymphocytic Leukemia (CLL)
MIX
P038-B1
VERSION
Vs. 21
DATE
27-10-2014
REGION
various
APPLICATION
Chronic Lymphocytic Leukemia (CLL)
MIX
P038-B1
VERSION
Vs. B1-01
DATE
06-02-2020
REGION
Various
APPLICATION
Chronic lymphocytic leukemia (CLL)