Service Hotline +49 7822 440150-0

MLPA® - MRC Holland Kits

Please note before download:

  • Mix descriptions are only free of charge for customers with maintenance contract.
  • Don't hesitate to contact us, if there are any mix descriptions missing on this website.

  • To set up a new mix descriptions for you, still available at MRC Hollands website, please provide us the name of the mix (e.g. P002-D1), the version of the mix (e.g. Vs.02) and the date of its release.

  • To set up a new mix descriptions for you, not available at MRC Hollands website any more, please provide us the corresponding document by email or fax (+49-7822-440150-20).

Download

  • log into your SEQUENCE Pilot installation
  • go to category MLPA®
  • go to operation Mixes [master file]
  • press button [Import] and select the downloaded mme-file
  • if the corresponding mix already exists in your SEQUENE_PILOT installation you will be asked "Do you want to save the mix with a new name / lot?"; please press button [Yes] and complete the fields in the following dialogue; press button [OK] to save your entries
  • if the mix doesn't exist yet just press button [OK] in the following dialogue
MIX
VERSION
DATE
REGION
APPLICATION
DOWNLOAD
MIX
P360-B1
VERSION
Vs. 10
DATE
06-04-2018
REGION
Chromosome Y
APPLICATION
Y-Chromosome Microdeletions
DOWNLOAD
MIX
P360-B2
VERSION
Vs. B2-01
DATE
20-03-2019
REGION
Chromosome Y
APPLICATION
Y-Chromosome Microdeletions
DOWNLOAD
MIX
P360-B2
VERSION
Vs. B2-02
DATE
30-11-2022
REGION
Chr. Y
APPLICATION
Y-Chromosome Microdeletions
DOWNLOAD
MIX
P361-A2
VERSION
Vs. 05
DATE
06-04-2016
REGION
USH2A 1q41
APPLICATION
Usher syndrome
DOWNLOAD
MIX
P361-A3
VERSION
Vs. A3-01
DATE
15-07-2019
REGION
USH2A 1q41
APPLICATION
Usher syndrome type II (USH2)
DOWNLOAD
MIX
P362-A2
VERSION
Vs. 05
DATE
06-04-2016
REGION
USH2A 1q41
APPLICATION
Usher syndrome
DOWNLOAD
MIX
P362-A3
VERSION
Vs. A3-01
DATE
15-07-2019
REGION
USH2A 1q41
APPLICATION
Usher syndrome type II (USH2)
DOWNLOAD
MIX
P365-A1
VERSION
Vs. 01
DATE
04-03-2010
REGION
7p, 15q-cen, 16p, 21q-cen, 21q
APPLICATION
Subtelomere screening
DOWNLOAD
MIX
P365-A2
VERSION
Vs. 07
DATE
03-12-2014
REGION
7p, 15q-cen, 16p, 21q-cen, 21q
APPLICATION
Subtelomere screening
DOWNLOAD
MIX
P366-A2
VERSION
Vs. 06
DATE
23-10-2015
REGION
CHM-RP2-RPGR
APPLICATION
Retinitis pigmentosa (RP)
DOWNLOAD
MIX
P366-A2
VERSION
Vs. 07
DATE
12-12-2017
REGION
CHM-RP2-RPGR
APPLICATION
Retinitis pigmentosa (RP)
DOWNLOAD
MIX
P366-B1
VERSION
Vs. B1-01
DATE
20-05-2022
REGION
RP2 Xp11.3; RPGR Xp11.4; CHM Xq21.2
APPLICATION
Retinitis pigmentosa, X-linked (xlRP); Choroideremia
DOWNLOAD
MIX
P367-A2
VERSION
Vs. 08
DATE
02-06-2017
REGION
BEST1 (=VDM2), PRPH2 (=RDS)
APPLICATION
Macular Dystrophy, Vitelliform
DOWNLOAD
MIX
P367-A3
VERSION
Vs. A3-01
DATE
28-06-2018
REGION
BEST1 (=VDM2), PRPH2 (=RDS)
APPLICATION
Macular Dystrophy, Vitelliform
DOWNLOAD
MIX
P367-A3
VERSION
Vs. A3-02
DATE
23-02-2022
REGION
BEST1 11q12.3; PRPH2 6p21.1
APPLICATION
Best vitelliform macular dystrophy (VMD2); Vitelliform macular dystrophy type 3 (VDM3)
DOWNLOAD
MIX
P368-B1
VERSION
Vs. 03
DATE
06-09-2011
REGION
10p13; DCLRE1C
APPLICATION
SCID and Omenn syndrome
DOWNLOAD
MIX
P368-B1
VERSION
Vs. B1-01
DATE
29-05-2018
REGION
DCLRE1C 10p13
APPLICATION
Severe combined immunodeficiency (SCID), Athabaskan-type; Omenn syndrome
DOWNLOAD
MIX
P368-B1
VERSION
Vs. B1-02
DATE
13-12-2021
REGION
DCLRE1C 10p13
APPLICATION
Severe combined immunodeficiency (SCID), Athabaskan-type; Omenn syndrome
DOWNLOAD
MIX
P369-A1
VERSION
Vs. 02
DATE
21-12-2012
REGION
17p11.2
APPLICATION
Smith-Magenis syndrome
DOWNLOAD
MIX
P369-A2
VERSION
Vs. 04
DATE
21-08-2015
REGION
17p11.2
APPLICATION
Smith-Magenis syndrome
DOWNLOAD
MIX
P370-A1
VERSION
Vs. 04
DATE
24-12-2011
REGION
BRAF, IDH1, IDH2
APPLICATION
Gliomas
DOWNLOAD
MIX
P370-B1
VERSION
Vs. 06
DATE
16-09-2014
REGION
BRAF, IDH1, IDH2
APPLICATION
Gliomas
DOWNLOAD
MIX
P370-C1
VERSION
Vs. C1-01
DATE
23-04-2020
REGION
BRAF 7q34; IDH1 2q33.3; IDH2 15q26.1; FGFR1 8p12; MYB 6q23.3; MYBL1 8q13.1; CDKN2A 9p21.3
APPLICATION
Gliomas
DOWNLOAD
MIX
P371-A1
VERSION
Vs. 01
DATE
25-12-2008
REGION
2p16, Langer Giedion, 9q22, WAGR, 15q24, 17q21
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P371-B1
VERSION
Vs. 07
DATE
10-04-2014
REGION
2p16, Langer Giedion, 9q22, WAGR, 15q24, 17q21
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P372-A1
VERSION
Vs. 05
DATE
09-03-2012
REGION
Sotos, DiGeorge, Rubinstein-Taybi, NF1
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P372-B1
VERSION
Vs. 07
DATE
13-11-2013
REGION
Sotos, DiGeorge, Rubinstein-Taybi, NF1
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P373-A1
VERSION
Vs. 03
DATE
18-08-2009
REGION
1p36, 3q29, Wolf-Hirschlorn, Cri du Chat, Phelan-McDermid
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P373-B1
VERSION
Vs. 09
DATE
13-11-2013
REGION
1p36, 3q29, Wolf-Hirschlorn, Cri du Chat, Phelan-McDermid
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P373-C1
VERSION
Vs. 15
DATE
05-10-2018
REGION
Region 1p36; 3q29; 4p16.3; 5p15.2; 22q13.33
APPLICATION
Microdeletion follow-up: 1p36 Deletion syndrome; 3q29 Microdeletion syndrome; 3q29 Microduplication syndrome; Wolf-Hirschhorn syndrome; Cri du Chat syndrome; Phelan-McDermid syndrome
DOWNLOAD
MIX
P374-A1
VERSION
Vs. 06
DATE
24-02-2014
REGION
7q11, PWS/AS, Miller-Dieker, Smith-Magenis, RETT
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P374-B1
VERSION
Vs. 07
DATE
30-01-2017
REGION
7q11, PWS/AS, Miller-Dieker, Smith-Magenis, RETT
APPLICATION
Microdeletion follow-up
DOWNLOAD
MIX
P376-B2
VERSION
Vs. 04
DATE
01-03-2013
REGION
BRCA1ness
APPLICATION
BRCA1-mutated and sporadic tumours with BRCA1-like genomic profile
DOWNLOAD
MIX
P376-B4
VERSION
Vs. B4-01
DATE
18-03-2021
REGION
various
APPLICATION
BRCA1-like breast cancer profile
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-01
DATE
23-02-2018
REGION
1p34
APPLICATION
Colon cancer, stomach cancer (hereditary)
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-02
DATE
29-01-2019
REGION
MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
APPLICATION
MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1)
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-03
DATE
29-04-2020
REGION
MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
APPLICATION
MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1)
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-04
DATE
26-07-2021
REGION
MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
APPLICATION
MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1)
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-05
DATE
09-11-2021
REGION
MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
APPLICATION
MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1)
DOWNLOAD
MIX
P378-D1
VERSION
Vs. D1-06
DATE
06-10-2022
REGION
MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
APPLICATION
MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1)
DOWNLOAD
MIX
P379-A1
VERSION
Vs. 03
DATE
21-12-2012
REGION
NRXN1
APPLICATION
Pitt-Hopkins-like syndrome 2
DOWNLOAD
MIX
P379-A2
VERSION
Vs. 04
DATE
12-05-2015
REGION
NRXN1
APPLICATION
Pitt-Hopkins-like syndrome 2
DOWNLOAD
MIX
P379-A2
VERSION
Vs. A2-01
DATE
24-12-2018
REGION
NRXN1 2p16.3
APPLICATION
Pitt-Hopkins-like syndrome 2
DOWNLOAD